Dr. Mario Izurieta Ulloa
Neurosurgeon
Hospital Luis Vernaza
Hospital Alcívar

Chimborazo 3310 y Azuay
1st. Floor office 2
Guayaquil, Ecuador

Oficina: +593 4 2584661
Celular: +593 9 7195100
mizuriet@gye.satnet.net

 

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Stem Cell Implantation - Cellular Therapy

All mammals begin as two cells -- sperm and egg -- that combine into a single cell. This single cell will divide exponentially into specialized cells making up various organs and systems -- all the tissues of a new organism.

A stem cell is an immature cell that can become a different cell, or perhaps become one of many different cells. Most stem cells also can renew themselves -- divide -- indefinitely. These two characteristics are what present a new pathway to repairing damage to the human body caused by trauma, degeneration and disease. The stem cells are the precursors of all the cells of tissues. The regeneration of the structures of the nervous system has been considered, formerly, as impossible. At the present time, the concepts have changed based on experimental studies in animals of laboratories and human studies.

There are different fields in which stem cells are changing the concepts in tisular regeneration. Spinal cord injury, Parkinson''s disease, Alzheimer''s disease, ALS (amyotrophic lateral sclerosis) and heart disease are some of the devastating disorders for which stem cell research holds the promise of treatment, and perhaps one day, cure.

The last more promising advances in the field of research in the Spinal Cord Injury have been obtained through the use of stem cells originating from the umbilical cord or the bone marrow of the patients.

The Spinal Cord Injury has been considered, for many decades, as a challenging pathology to the Neurosurgeon. Millions of dollars have been invested on research for the treatment of the Spinal Cord Injury through medical protocols as the use of metylprednisolone, naloxone, etc., as well as different surgical treatments like the early decompression, the revascularization using epiplon, etc. Awfully, none of these therapeutic alternatives has offered encouraging results for the creation of a treatment guide.

The Junta de Beneficiencia de Guayaquil, Department of Regenerative Medicine at Luis Vernaza Hospital has begun the research for implantation of Bone marrow stem cell in different pathologies such as:

  1. Spinal Cord Injury
  2. Parkinson Disease
  3. Esclerosis lateral amyotrophic

And some other diseases considerated as incurable.

The preliminary results of the patients with Spinal Cord Injury show important changes in the patients soon after implantation and a rigorous program of physical therapy, mainly at the level of proximal movement of lower extremities, control of sphincters and vegetative functions.

These results have been presented in the Congress of the International Society for Cellular Therapy (ISCT) carried out at Sydney, Australia and Congress of Neurological Surgeons at San Diego, California in September 2007.

Next, a few more details about this investigation presented during the 2007 Congress of Neurological Surgeons celebrated at San Diego, California.

Interview to our patients:

 

 © 2007 - 2011. Dr. Mario Izurieta Ulloa.